In lung cancer, H19 downregulation significantly reduces clonogenicity and anchorage-independent growth, and it acts as a critical downstream effector of c-Myc to promote tumorigenesis [99,100,101]
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Therapeutic Research Protocol Dose: 0.3 0.5 mg (= 1220 clicks) Duration: 3 5 weeks Frequency: Daily, evening administration Cycle Interval: 3 4 weeks off before repeating Goal / Description: Higher-dose model for stress-response and neuroendocrine regulation studies
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185 GM-CSF derived from breast cancer tumor cells can promote ARG1 expression in tumor-infiltrating myeloid cells through STAT3 and p38 MAPK signaling pathways, enhance the function of tumor-infiltrating myeloid cells, and promote the development of immunosuppressive TME (Fig
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