Starting BMI 37.3 @ADA_DiabetesPro @AmDiabetesAssn Up to 24% weight loss @AniaJastreboff #ADA2023 presents the primary efficacy data for #weightloss for the Glucagon-GLP-1-GIP receptor tri-agonist for PPL with #obesity over 24-48 weeks
To date there are no data on the impact of this type of drug on the reproductive male system, however studies in PCOS women with licogliflozin, a dual SGLT1/2 inhibitor, showed an amelioration of hyperinsulinmeia and hyperandrogenism, but not of T levels, without any effect on body weight (58)
In practice, it's considerably more complicated
Over five years, non-GLP-1 spending increases by $6,800, or 30 percent of the amount spent on GLP-1s
Brian Wang is a Futurist Thought Leader and a popular Science blogger with 1 million readers per month
Each comes with its own dosing and indications