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We conducted a randomized, double-blind, placebo-controlled multiple ascending dose phase 1 study at a single center in the Republic of Korea in adults with overweight (BMI 2530 kg/m)

Miura S et al

[DOI] [PubMed] [Google Scholar] 89.Eftekharpour E., Fernyhough P

& Tordera, R

These data suggest that GLP-1 can promote the differentiation of pre-3T3-L1 adipocytes by promoting the expression of the specific markers LPL and AP2, as well as the transcription factors PPAR and C/EBP

In keeping with GLP1-mediated brain targeting, quantitative proteomics reveals changes in common and distinct hypothalamic pathways in response to GLP1/E between the two PCOS models, as basis for differential efficiency