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Vaccination (HBcAg): not routinely used in HBV testing Hepatitis B core antibody (anti-HBc): Corresponding antibody to HBcAg Common screening Screening Preoperative Care parameter indicating contact to HBV Total Anti-HBc: does not differentiate between acute, chronic, or past infection AntiHBc-IgM: acute HBV infection AntiHBc-IgG: always detectable after contact to HBV (unspecific) Hepatitis B envelope Envelope Bilayer lipid membrane acquired by viral particles during viral morphogenesis