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this result was observed regardless of baseline CV risk profile, with no significant differences between subgroups (p = 0.25 for interaction between subjects with prior MI or stroke vs no prior MI or stroke and p = 0.27 for interaction between subjects with established CVD vs CV risk factors only)

The most commonly reported side effect is nausea, especially in the first hour after a dose

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Compared to ApoE3 knock-in controls, ApoE4-KI mice exposed to cadmium display more severe gut microbiota dysbiosis and greater hepatic dysfunction

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