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A study from January 2026 looked at the impact of treating obesity in Medicaid patients

demonstrated that Angelica polysaccharide exerts anti-inflammatory effects by inhibiting the TLR4/MyD88/NF-B signaling pathway, and notably, the serum metabolite 5-methyl-dl-tryptophan (5-MT) was restored by Angelica polysaccharide treatment (Zou et al., 2023)