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PLoS ONE (2014) 9:e87488

Retrieved July 27, 2026 from www.sciencedaily.com

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Co-administration of SGLT2 inhibitors with GLP1-RA reduces body weight by 4.5 kg at 24 weeks of treatment, and this weight loss is maintained for up to 1 year ( 5.7 kg) in obese individuals without diabetes [21, 30]

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Roche explicitly stated that petrelintide has the potential to be used alone or combined with the GLP-1/GIP dual agonist CT-388 in a fixed-dose combination