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Cox proportional hazards models were used to evaluate the association between GLP-1 RA use and osteoporosis risk, adjusting for age, sex, BMI, blood pressure, lipid profile, renal function, osteocalcin, vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status

Patients who used Ozempic were categorized into cohorts based on when they discontinued Ozempic before surgery: 30 days prior to surgery 482 patients 14 days prior to surgery 591 patients 7 days prior to surgery 680 patients 5 days prior to surgery 758 patients 3 days prior to surgery 777 patients 1 day prior to surgery 706 patients Did not stop Ozempic prior to surgery 170 patients These patients were compared to a control group of 206,005 with no history of Ozempic use

Rigby MR, Harris KM, Pinckney A et al (2015) Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients