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151 Single-cell RNA sequencing of ~50,000 transcriptomes from young (3 - 4 months) and old (2123 months) mice demonstrated substantial regional heterogeneity of age-dependent changes indicating that ageing of neurones and glia may develop through distinct molecular pathways

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Similarly, an increase in lipid peroxidation levels and a decrease in GSH levels could also be detected in the same above model ( in vivo and in vitro (Seibt et al., 2019)