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In mice subjected to transverse aortic constriction (TAC), a model of pressure overload-induced heart failure, cardiomyocytes exhibit severe hypertrophy and mitophagy activation

45,46 As shown in Figure 2 , GLP-1RAs penetrate the blood-brain barrier and directly activate GLP-1 receptors in the hypothalamus, especially within the ARH nucleus, a key center for appetite regulation

Beard density potentially improved

doi:10.1016/j.lfs.2013.03.008

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