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Este proceso es muy importante, sobre todo durante periodos de baja disponibilidad de carbohidratos o durante el ejercicio prolongado, ya que el cuerpo recurre a las grasas como fuente de energa primaria para preservar las reservas de glucgeno

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In addition, the dual InsR/IGF-IR inhibitor linsitinib can prevent the emergence of breast cancer cells that are resistant to long-term estrogen deprivation or antiestrogen treatment and inhibit growth of established ER+ breast cancer xenografts in ovariectomized mice [107]

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