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Licensed indications The licensed indications for ACE-Is vary between class members but include: Hypertension: alone or in conjunction with other antihypertensive agents

Semaglutide is licensed to treat both obesity and type 2 diabetes in the UK, with weight loss licensing being a very recent development

Titration the practice of starting at a low dose and gradually increasing it over several weeks is a standard approach with incretin-based therapies, as it allows the gastrointestinal system to adjust and reduces the severity of nausea, vomiting, and other early side effects

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