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Providers treating transgender patients for gender-affirming hormone therapy should use Z87.890 (Personal history of sex reassignment) as a secondary code while E29.1 remains the primary diagnosis for reimbursement purposes

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Those taking multiple medications should consult their healthcare provider before initiating berberine supplementation

The development of anti-cagrilintide antibodies has been observed in 46-73% of patients by week 26, with higher rates associated with longer treatment duration and higher doses