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Similarly to other injections, it was prescribed to treat Type 2 Diabetes, but in December 2024 was approved to treat obesity on the NHS.[5] Potential Side Effects and Risks Although GLP-1 drugs for diabetes and weight loss have proven to be effective, they do have side effects and the most common are: [3] Nausea and vomiting Constipation Diarrhoea Fatigue Indigestion Risk of low or high blood sugar Because GLP-1 receptor agonists mimic a natural gut hormone, the most common side effects are gastrointestinal including nausea, vomiting, diarrhoea, and a feeling of early fullness
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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist , originally developed by the Danish pharmaceutical company Novo Nordisk
This is why many individuals find that long-term use aligns with their weight loss goals rather than viewing it as a temporary intervention