fda approval semaglutide mash Novo Nordisk's Wegovy gets accelerated US for liver disease FDA grants the first GLP-1

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These results were attributed not just to improved glycemic control, but to anti-inflammatory effects on arterial walls, reduced plaque formation, and enhanced endothelial function

These investigations provide insights into the metabolic regulation of contractile adaptation and the cellular mechanisms underlying activity-induced metabolic remodeling in muscle tissue across different experimental conditions

The primary endpoint and all key secondary endpoints of the study were successfully achieved in 2024