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Some studies have shown that the most effective doses might be between 500 and 600 milligrams a day, but people taking dosages as small as 120 milligrams a day have also reported benefits

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Warning signs requiring prompt medical attention include severe, persistent upper abdominal pain (which may indicate pancreatitis or gallbladder disease), persistent vomiting, signs of dehydration, jaundice (yellowing of skin/eyes), or inability to tolerate oral intake

Additional analyses demonstrated that oral semaglutide 7 mg was associated with improvements of 0.11 QALYs and increased costs of EUR 226 versus sitagliptin and was therefore associated with an ICER of EUR 2011 per QALY gained