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Monitoring and Medical Supervision: While AOD-9604 has a favorable safety profile, medical supervision is recommended, particularly for individuals with pre-existing health conditions

Other evidence also suggests that GLP-1R in the cerebral cortex affects hedonic feeding by targeting areas involved in reward and addiction (110)

Monitoring compliance on a regular basis assists to detect possible problems before they lead to audit or punishment

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Thus, MB is generally contraindicated or avoided with serotonergic drugs, and if MB must be given, those medications should be discontinued well in advance or not started until sufficient time has passed after MB dosing

In the long-term, these dynamics are likely to partially or fully resolve