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Three pharmacokinetic (PK) studies (total of 30 patients) have suggested that those with Gilberts syndrome have lower paracetamol glucuronidation [28, 33, 34]

J Neurochem 2008

BK: Supervision, Writing original draft, Resources, Writing review and editing, Investigation, Project administration, Methodology, Conceptualization

Many of these symptoms are also present in the thiamine deficiency states (137), supporting involvement of ACP2 in thiamine metabolism

IV therapy is particularly helpful for those with absorption issues, chronic illness, or the need for rapid hydration

Unless it is wrapped in a protective delivery system, its effectiveness is often limited