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Generally, those with fair to medium skin tones may notice a shift within 1 to 3 months

This means vial consumption is much faster, and the math around vial life looks completely different

doi: 10.1016/j.autrev.2018.01.009 31 BrittainEMuirheadNFinlayAYVyasJ

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Ive seen that people who have chemical sensitivities/multiple allergies, as well as histamine intolerance, often do really well with my liver protocol (or something similar) before diving into a gut support protocol like the one I outlined in Hashimotos Protocol , with modifications to avoid consuming high histamine foods (bone broth and fermented veggies, which are typically great for supporting the gut, are both high histamine foods)