5.6 Severe Gastrointestinal Adverse Reactions Use of RYBELSUS has been associated with gastrointestinal adverse reactions, sometimes severe [see Adverse Reactions (6)]
The glycosylation of the mucins also provides a physical and electrochemical barrier as the sugars interact with moieties on the surface of bacteria and viruses to bind and hold them in place slowing diffusion rates and reducing the effectiveness of microbial motility (McAuley et al., 2017
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To achieve this, a group of 64 young and aged rats were allocated into groups, all of which would receive either a low or high dose of caffeine or paraxanthine, respectively
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