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Enzyme Activation: cAMP activates protein kinase A, which phosphorylates hormone-sensitive lipase and perilipin proteins surrounding lipid droplets

Nisenblat V, Prentice L, Bossuyt PM, Farquhar C, Hull ML, Johnson N

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The activity of the phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) pathway and the expression of peroxisome proliferator-activated receptor coactivator-1 (PGC-1) were verified by Western blot