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[] Figure 5 illustrates the principal findings of this narrative review

& Overbeek, P

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CPT1 exists in two isoforms, CPT1A and CPT1C, with CPT1A being a rate-limiting enzyme that forms a hetero-oligomeric complex crucial for the acylcarnitine shuttle

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It has been found that smooth muscle cells in COPD patients exhibit mitochondrial dysfunction, which in turn causes an increase in mitochondrial ROS, resulting in an oxidative-oxidative imbalance that contributes to the development and progression of COPD