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These biomarkers underscore their indispensable role in early diagnosis, disease progression monitoring, and as targets for therapeutic intervention

Strengths: Highest documented bioavailability Dose delivery is reliable and predictable Compatible with published dosing protocols Well-documented safety profile Limitations: Requires patient willingness and capability for self-injection Needles, disposal, and injection-site considerations Requires refrigerated storage for most preparations Oral Spray: A Growing Alternative Oral spray formulations deliver peptide into the oral cavity, with absorption occurring through the oral mucosa and variably through ingestion with subsequent partial degradation

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