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It is not appropriate for individuals with active cancer, certain pituitary conditions, or other contraindications

In some cases, the payer may deny it because it should have been included in an evaluation and management (E/M) visit

The 60% power contemplated requires a sample size of 304 patients (152 in each arm) higher powers would increase the sample size required and the enrolment of such numbers cannot be guaranteed

Typically, 3-5 sessions are recommended for optimal results

Oral administration of ALC decreased VAS scores significantly

Acetylcarnitine belongs to a class of fatty acid metabolites called acylcarnitines, which are produced by the conjugation of fatty acids with l-carnitine, a physiological process essential for the transport of fatty acids into mitochondria for -oxidation and ATP production [3, 29]