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Cell Metab [Internet] 27(4):74056

Quick summary: Part 1 Prevalence & Demand: Single largest patient population of any chronic disease in the country Traditionally marginalized groups are more affected by it The numbers are growing Patients want a solution desperately Clinical Efficacy: Clinical trial data suggest benefits outweigh risks for certain patient populations Actions of healthcare providers suggest they strongly want patients to have access Pricing Timeline: Branded drug will start with monopolistic prices for ~decade The patent will eventually expire The bigger the market (outlined above), the more competition, the greater the percentage price decrease Adding up the above, over a long enough time period, the price will come down to a very affordable price based on the current size of the market

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Pharmacogenetics of the G protein-coupled receptors

Many patients reach the maintenance phase after several months of gradual increases, depending on tolerance and progress