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Body composition, including changes in lean and fat mass, indicates metabolic enhancement

while animal experiments suggest that increasing dietary leucine intake can reduce diet-induced obesity and improve glucose and cholesterol metabolism through multiple mechanisms (140), indicating the complexity and dose-dependency of BCAA actions

16 In this paper, we use mathematical modelling and simulation to investigate the weight loss efficacy of GLP1 receptor agonists under alternative dosing regimens

The placenta and its mitochondria have a substantial ability to adapt to insult, and the adaptive capacity varies depending on when a challenge occurs and its duration [58, 59]

Iwamura et al., 2011

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