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Background Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies Review context for lean-mass and mitigation questions during GLP-1-based weight-loss treatment

The cardiovascular evidence is the most solid: in the SELECT trial, people with obesity and established heart disease who added semaglutide cut their risk of cardiovascular death, a second stroke, or a second heart attack by about 20%

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Posted November 30, 2025 in Fertility Blog & Information 17 minute read Key Takeaways Weight loss enhances fertility by restoring ovulation, reducing pregnancy complications, and increasing rates of spontaneous conception

Tylka TL, Homan KJ

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