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[DOI] [PubMed] [Google Scholar] Soltwisch J., Kettling H., Vens-Cappell S., Wiegelmann M., Muthing J., Dreisewerd K

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To facilitate regulatory approval and clinical adoption, future research should focus on standardized formulation strategies, robust pharmacokinetic profiling (including C_max, AUC, and tissue distribution), long-term reproductive safety studies, and carefully planned randomized controlled trials comparing nanoformulations with both free phytochemicals and standard-of-care therapies

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