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doi: 10.1186/1750-9378-4-S1-S2 30 PichardoCMEzeaniAAcevedoAMAgurs-CollinsTBailey-WhyteMDorseyTHet al

Because theyre absorbed through the nasal passages, many patients notice effects faster than with oral treatments

However, if it has been exposed to temperatures above 80F for more than a few hours, or if you are uncertain about the exposure time, it is safer to discard the medication and request a replacement

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These re-analyses highlight limitations in the original studys conclusions, including potential underemphasis of subgroup effects, dose-response relationships, and long-term implications