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10.1038/mp.2016.68 [DOI] [PMC free article] [PubMed] [Google Scholar] 83.Zarate C, Machado-Vieira R, Henter I, Ibrahim L, Diazgranados N, Salvadore G

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Perimenopause lasts up until menopause, when a womans ovaries stop releasing eggs and they stop having menstrual cycles

Antiobesity drugs act via any of four mechanisms: 1) decreasing energy intake, 2) increasing energy expenditure or modulating lipid metabolism, 3) modulating fat stores or adipocyte differentiation, and 4) mimicking caloric restriction

In contrast, gastrointestinal side effects were reported in 10 of the 11 studies and were consistently more common in the intervention groups