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Grape seed procyanidin activates peroxisome proliferator-activated receptor (PPAR), thereby downregulating the expression of cyclooxygenase 2 (COX-2), achieving the regulation of lipid metabolism, inhibiting cell proliferation, blocking the inflammatory cascade, alleviating vascular inflammation, and reversing the vascular structural remodeling of PASMCs (Liu et al., 2020)

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These encounter characters work alongside S codes, which are injury nature codes