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The hepatic iron deposition is primarily attributed to low levels of ceruloplasmin [21] , a ferroxidase that facilitates iron storage in tissues, similar to what occurs in hemochromatosis [52]

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It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide using S-adenosylmethionine as the methyl donor

How a researcher divides it depends entirely on reconstitution