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Since RPSMC can be transfected with reporter constructs of the rat AR promoter and the AR coding region (Shen, Marquez, Rajfer, Gonzalez-Cadvid, unpublished), it should be possible to detect factors able to regulate AR expression and to determine whether AR hyperexpression stimulates androgen-dependent cell proliferation
and persistent changes in neurotransmitter dynamics initiated during the brief active window
Gaba et al., 2020)
Then, you see your doctor for a routine physical, and youre suddenly diagnosed as having atherosclerosis