For example, suppose your goal is to lose one pound per week
If you have primary hyperoxaluria, as diagnosed by a doctor, be sure to check with your provider about new therapies, such as siRNA therapies that have been recently approved
Injectable Wegovy: Average weight loss: about 15% of starting body weight over 68 weeks Studied in the STEP 1 trial with over 1,900 adult participants Participants combined the injection with a reduced-calorie diet and increased physical activity Oral Wegovy pill: Average weight loss: about 14% of starting body weight over 64 weeks Studied in a separate 205-person clinical trial Similar lifestyle requirements were applied to both clinical studies The difference between the 2 studies is small, but they were not a direct head-to-head comparison
Providers should confirm no contraindications exist, including personal or family history of medullary thyroid carcinoma, which remains a contraindication for GLP-1 agonist use regardless of thyroidectomy status
Farney et al
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