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In contrast to class I GRXs, which are glutathionylated at Cys A over a wide range of GSH/GSSG redox potentials, only the internal disulfide-containing oxidized form is detected for ROXY9 at a midpoint redox potential between 220 and 230 mV at p H 7.0

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In addition to ICP27, the viral protein pUL69 is an ICP27 homologue and multifunctional RNA export factor encoded by the beta-herpesvirus human cytomegalovirus (HCMV)

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