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doi: 10.1016/j.ijscr.2025.111006 29 RafeyMFButtACoffeyBReddingtonLDevittALappinDet al

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Notably, DPP-IV targets include cytokines, growth factors, and neurotransmitters, in addition to islet-derived peptide hormones, indicating that the improvements in beta-cell function in response to DPP-IV inhibition may also be mediated by other intra-islet paracrine signaling factors

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