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A genome-wide methylome analysis found the expression of ATF3, suppressing the system Xc by binding to the SLC7A11 promoter (Wang et al., 2020), is higher in PE placenta than the normal placenta (Ching et al., 2014)

Binding of Prx1 to long non-coding RNA LncFASA leads to phase separation, formation of Prx1-containing condensates, and subsequently ferroptotic cell death in triple-negative breast cancer [146]

Frequency varies depending on individual needs, treatment goals, and provider guidance

Sloan P, Gale N, Hunter K

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