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Their advantageous properties, including low molecular weight, minimal immunogenicity, facile chemical synthesis, robust tissue penetration, and an expansive target scope, position them as compelling alternatives to antibodies for addressing the cardinal limitations of PROTACs, namely poor selectivity, off-target toxicity, and inadequate delivery efficiency (Fig

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Senescent oocyte-surrounding cumulus granulosa cells release soluble FasL (sFasL), which binds to Fas receptors on oocytes (Matsuda-Minehata et al., 2006

[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Gnad T, Scheibler S, von Kugelgen I, Scheele C, Kilic A, Glode A, et al

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