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Nevertheless, the current study did not employ advanced analytical techniques, such as high-performance liquid chromatography (HPLC) or amino acid profiling using dedicated analyzers, to confirm and quantify these modifications

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In conclusion, numerous mechanisms may be involved in the antiviral effect of lactobacilli towards HSV-2: interference with early steps of virus infection (binding/entry), production of metabolites with a direct antiviral effect (lactic acid, hydrogen peroxide) and production of compounds able to inhibit intracellular events of virus replication