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Given that EtOH-induced mitochondrial dysfunction and ER stress are intimately involved in the pathogenesis of ALD, future studies to examine these pathways under the current experimental setting will provide important mechanistic information underlying the protection seen in GCLM KO mice

& Feinglos, M

In PTC and anaplastic thyroid carcinoma, somatic KEAP1 and NFE2L2 mutations activating the Nrf2 pathway were discovered (128, 129)

Storage Conditions: Keep tightly closed and store at 5-30C (41-86F)