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[127] [128] Synthesis [edit] Biosynthesis [edit] Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III

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It was identified before GLP-1 and was actually the first incretin hormone described in the literature