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The 48-week retatrutide curve had not plateaued at readout, so the 24.2% figure likely under-represents the 72-week steady state that would match SURMOUNT-1's window [1]

Since Semaglutide works by altering hormone levels, specifically GLP-1 (glucagon-like peptide-1), it may interfere with the hormonal environment that is crucial for healthy fetal growth

We think thats a signal worth investigating. Studying Social Media for Health In 2011, Ungar participated in one of the earliest efforts to mine online, user-created content for information about drugs adverse effects

Anti-inflammatory action: GIP signaling suppresses inflammatory factor release (e.g., IL-6, TNF-), while GCGR activation promotes chondrocyte proliferation

Diabetologia 52 , 1730 (2009)

Eur J Pharmacol (2012) 691(1-3):2926