ATP production in the cells in the penumbra is reduced by ~5070%, which supports some semblance of ion homoeostasis
Chen YB, Rahemtullah A, Hochberg E
Consequently, GST activity reduction leads to the accumulation of ROS in inflamed lesions, as it was reported in psoriatic plaques, where ROS levels are 3-fold higher than in non-lesioned skin (64)
A randomized controlled trial published in the European Journal of Nutrition found that daily consumption of oral glutathione at 1,000 mg increased blood glutathione levels by 30-35% in red blood cells, plasma, and lymphocytes after 6 months of supplementation
Overall, characterization of PRO measures across the BSA spectrum showed that the burden of psoriasis was similar in patients with low, medium, and high BSA involvement at the time of initiating biologic therapy, suggesting that treatment decisions are being made to use biologics in appropriate patients with low BSA involvement
Glutathione fights free radicals that cause skin aging and dark spots
