retatrutide type 2 diabetes trial results 2024 💉 may be redefining obesity treatment. New data from TRIUMPH-1 showed: 🔥 ~28% average weight loss over 80 weeks 🔥 >30% weight loss in nearly half of participant #ObesityMedicine #Retatrutide #GLP1 #CardioMetabolic Phase III retatrutide study demonstrates

It is notable that neither the GLP-1R antagonist exendin(939) nor the GRA REMD2.59 had any (major) effect on glucagon secretion at 1 mmol/l glucose, making it unlikely that glucagon secretion is under significant autocrine control by glucagon or GLP-1(736) [63, 64] from alpha cells

Cortisol secretion through ACTH (adrenocorticotropic hormone) stimulation and prolactin release through dopamine receptor interaction

Salman, M

Theres a pretty high percentage of people that when you give them these medications, they just really have no effect from them no real change in appetite and no meaningful weight loss, he says

Results GLP-1 RA treatment consistently reduced body weight, BMI, and waist circumference across all time points

I was hoping it would help when I started the GLP-1.