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[Updated 2019 May 4]

This leads to the stiffening of arteries, increased blood pressure, and inflammation, all of which contribute to cardiovascular complications

And although APOE4 is a bigger risk factor for Alzheimers than is APOE3 , and Alzheimers involves cognitive decline, among infected Tsimane Amazon-Indians, APOE4 is associated with better cognition than APOE3 (Trumble et al., 2017

NC), confirming its role as a stress-responsive biomarker