All serious or unexpected adverse reactions (especially allergic responses) should be reported and the therapy re-evaluated
This pathway is considered the most genotoxic as the 4-OH estrogen metabolites can become reactive quinones that have the potential to bind to DNA and form damaging (unstable) depurating adducts, that may increase risk for cancer, such as breast and prostate cancer
GI side effects may worsen, and clearance is unknown
212 For example, a study conducted in the United Kingdom, where B 2 fortification is not mandatory, examined B 2 intake in 407 healthy subjects aged 1892 years old and found 29% were not achieving required intake levels
Khavinson VKh, Konovalov SS, Yuzhakov VV, Popuchiev VV, Kvetnoi IM
Let's drive the information, education, and oversight with a compounding pharmacy that manufactures compliantly anywhere." How to navigate this uncertain terrain Dr