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Comparison of the effects of ICV and iPVN pro-glucagon-derived and related products Comparison of the effects of ICV and iPVN proglucagonderived and related products on food intake in fasted rats
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When to Seek Medical Advice : Patients should contact their healthcare provider if they experience unexplained bone pain, height loss, or fractures with minimal trauma, as these may indicate significant bone loss requiring evaluation and intervention
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5,6 Additionally, high glucose levels negatively impact osteoblast function, contributing to bone defects partly through the production of advanced glycation end-products (AGEs), which upregulates sclerostin, an inhibitor of osteoblast activity
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