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[10] It is also common in African American, Saudi Arabian, Sardinian males, some African populations, and Asian groups

In most cases this is a protective response

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doi: 10.1016/S1471-4906(01)01955-X 89 LiuMLiuJHaoSWuPZhangXXiaoYet al

GHK-Cu has demonstrated anti-inflammatory properties in published research, and tolerability is generally favorable compared to retinoids or high-concentration alpha hydroxy acids

It stimulates metalloproteinase activity, the enzymes responsible for breaking down and remodeling damaged tissue, while simultaneously increasing anti-protease expression to prevent excessive tissue degradation