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Besides the direct cytotoxic and prooxidant effects of CP treatment, necroptosis could be induced indirectly through the combined action of cytokines, TNF-, TNF-related weak inducer of apoptosis, and IFN-, which were upregulated upon CP administration

Similarly, Jagetia et al

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VLP-S2 reduced viral replication in respiratory tissues in hamsters challenged with SARS-CoV-2 Beta, Delta, and Omicron BA.1 variants and against a pangolin coronavirus [164]

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means appreciating the need for ongoing medical supervision