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The authors suggested that the decrease in TFAM may reflect potentially unaltered mtDNA content in GHRKO mice (Gesing et al., 2013)

JACC: Basic to Translational Science , 8 , 255257

Cognitive Function and Neurodegenerative Disease Glutathione is found in significant concentrations in the brain, where it scavenges free radicals that contribute to neuronal damage

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It sits in the extracellular matrix and, upon injury or mechanical stress, binds to c-met receptors on muscle satellite cells, activating them from quiescence so they can multiply and rebuild muscle fibers